Cdkn2a ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCdkn2a ELISA Kit for Rat(Rattus norvegicus)

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Cdkn2a (Gene name),

Cyclin-dependent kinase inhibitor 2A, isoform 1 (Protein name ), CD2A1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Cdkn2a(P16ink4a);

Protein name:

Cyclin-dependent kinase inhibitor 2A, isoform 1;

Alternative:

p16-INK4a(p16;p16-INK4);Cyclin-dependent kinase 4 inhibitor A(CDK4I);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterodimer with CDK4 or CDK6. Predominamt P16 complexes contained CDK6. Interacts with CDK4 (both 'T-172'-phosphorylated and non-phosphorylated forms); the interaction inhibits cyclin D-CDK4 kinase activity. Interacts with ISCO2.

Function:

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

159

Sequence:

50:

100:

150:

159:

LRGQPPKQR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9R0Z3

KEGG:

rno:25163

Pfam:

PF12796

UniGene:

Rn.48717

String:

Q9R0Z3

Uniprot:

Q9R0Z3

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ELISA Kit for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

E0794h

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96T

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ELISA Kit for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

E0794r

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96T

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ELISA Kit for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

E0794m

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96T

CLIA Kit for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

U0794r

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96T

CLIA Kit for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

U0794h

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MSDS:

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96T

CLIA Kit for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

U0794m

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96T

Polyclonal Antibody for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

P0794Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

P0794Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Cat.:

P0794Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

Protein for Rat Cyclin-dependent kinase inhibitor 2A, isoform 1

R&D Technical Data

12% SDS-PAGE Analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Frequent aberrant methylation of p16INK4a in primary rat lung tumors."
Swafford D.S. , Middleton S.K. , Palmisano W.A. , Nikula K.J. , Tesfaigzi J. , Baylin S.B. , Herman J.G. , Belinsky S.A.
Mol. Cell. Biol.17:1366-1374(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
strain: Fischer 344/N.
tissue: Lung.
2.

Buckles L.K. , Shull J.D.
Submitted (2002-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: ACI/SegHsd.
strain: Brown Norway/SsNHsd.
strain: COP.
tissue: Spleen.

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